• Culture of Oral Mucosal Epithelial Cells for the Purpose of Treating Limbal Stem Cell Deficiency 

      Utheim, Tor Paaske; Utheim, Øygunn Aass; Khan, Qalbi; Sehic, Amer (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-03-01)
      The cornea is critical for normal vision as it allows allowing light transmission to the retina. The corneal epithelium is renewed by limbal epithelial cells (LEC), which are located in the periphery of the cornea, the limbus. Damage or disease involving LEC may lead to various clinical presentations of limbal stem cell deficiency (LSCD). Both severe pain and blindness may result. Transplantation ...
    • Drømmen om nye tenner 

      Jacobsen, Nils; Khan, Qalbi; Hensten, Arne (Journal article; Tidsskriftartikkel; Peer reviewed, 2021)
      Tannlegene vært opptatt av muligheten for å få dannet nye tenner lenge. Det har ført til et nøye studium av den embryonale tann- dannelsen for å kunne kopiere den eksperimentelt. Forskningen har imidlertid bare i liten grad kunnet anvende sine eksperimen- telle oppsett på mennesker, men har benyttet seg av dyr som mus, rotter, minigriser og hunder, enkelte ganger i kombinasjon med in vitro ...
    • Genetic Aspects of Dental Erosive Wear and Dental Caries 

      Tulek, Amela; Mulic, Aida; Runningen, Maria; Lillemo, Jannike; Utheim, Tor Paaske; Khan, Qalbi; Sehic, Amer (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-13)
      Objectives. &e present review aims to give an overview of the literature focusing on novel genetic aspects of dental erosion and dental caries. Once the tooth erupts into the oral cavity, the regenerative capability of enamel is fundamentally limited due to the loss of dental epithelium during eruption. &e susceptibility or resistance to dental erosion and caries is presumably a result of environmental, ...
    • Thrombospondin-1 Is Necessary for the Development and Repair of Corneal Nerves 

      Tatematsu, Yukako; Khan, Qalbi; Blanco, Tomas; Bair, Jeffrey A.; Hodges, Robin R.; Masli, Sharmila; Dartt, Darlene A. (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-10-16)
      Thrombospondin-1-deficient (TSP-1−/−) mice are used as an animal model of Sjögren’s Syndrome because they exhibit many of the symptoms associated with the autoimmune type of dry eye found in primary Sjögren’s Syndrome. This type of dry eye is linked to the inflammation of the lacrimal gland, conjunctiva, and cornea, and is thought to involve dysfunction of the complex neuronal reflex arc that ...